Sildenafil is often a powerful and selective inhibitor of cGMP-specific phosphodiesterase kind 5 (PDE5), and that is answerable for degradation of cGMP in the corpus cavernosum. The molecular construction of sildenafil is similar to that of cGMP and functions like a aggressive binding agent of PDE5 during the corpus cavernosum, leading to much more cGMP and amplified penile response to sexual stimulation.

Cialis migliora l’afflusso di sangue e rilassa la muscolatura della prostata e della vescica e ciò può ridurre i sintomi associati all’iperplasia prostatica benigna. Cialis ha dimostrato di migliorare questi sintomi urinari già 1-two settimane dopo l’inizio del trattamento.

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In uno studio clinico di confronto tra tadalafil 5 mg somministrato insieme a finasteride 5 mg nel trattamento dei sintomi dell’iperplasia prostatica benigna, non sono state identificate nuove reazioni avverse.

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Il tadalafil ha una durata d’azione superiore a quella del sildenafil e questo permette una sua singola somministrazione giornaliera.

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